If you cannot upload to an FTP server:

• Go to the Site Properties window and click on the Save Site button. (To get to the Site Properties window, first go to the Site Manager by clicking the "Sites" button). This will initiate FTP Connection Test. If the Write test has failed, you will have to contact the FTP site's administrator to request upload permission.
• Check all your server details carefully including the settings for the Initial Remote Directory and the Initial Local Directory.
• Check your server uses passive FTP.

See http://www.nch.com.au/kb/10047.html for more help troubleshooting ftp connection problems.